Factors behind embryonic stem cell state

An international collaboration has found for the first time that two new epigenetic regulators, TAF5L and TAF6L, maintain self-renewal of embryonic stem cells. The scientists also found that these proteins activate c-Myc (a well-known cancer gene), and its regulatory network. This is the first time scientists have been able to show what these regulators do and how they control gene expression.

Leave a Reply

Your email address will not be published. Required fields are marked *