Preventing the onset of schizophrenia in mouse model

Although predisposing processes occur earlier, schizophrenia breaks out at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed individuals. Using a genetic mouse model of schizophrenia, researchers from the FMI showed that, like in patients, characteristic network and cognitive deficits only emerge in adult mice. They then demonstrated that these deficits could all be permanently prevented by specific treatments during a late adolescence sensitive time window.

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