For the treatment of the following diseases in adults:
- cryptococcal meningitis;
- invasive candidiasis;
- mucous candidiasis, incl. oropharyngeal candidiasis, esophageal candidiasis, candiduria and chronic mucocutaneous candidiasis;
- chronic atrophic candidiasis of the oral cavity (associated with wearing dentures), when oral hygiene or local treatment is not enough;
- vaginal candidiasis, acute or recurrent, when local therapy is not applicable;
candidal balanitis when local therapy is not applicable;
- dermatomycosis, incl. dermatophytosis of the feet, dermatophytosis of the trunk, inguinal dermatophytosis, versicolor versicolor and cutaneous candidiasis, when systemic treatment is indicated;
- dermatophytosis of the nails (onychomycosis), when treatment with other drugs is not acceptable.
For the prevention of the following diseases in adults:
- relapses of cryptococcal meningitis in patients at high risk of relapse;
- relapses of oropharyngeal and esophageal candidiasis in HIV-infected patients with a high risk of recurrence;
- to reduce the frequency of recurrence of vaginal candidiasis (4 or more episodes per year);
- for the prevention of candidal infections in patients with prolonged neutropenia (such as patients with hematological malignancies undergoing chemotherapy or patients undergoing hematopoietic stem cell transplantation).
Fluconazole is indicated for the treatment of children.
Fluconazole is used to treat mucous candidiasis (oropharyngeal candidiasis and esophageal candidiasis), invasive candidiasis, cryptococcal meningitis, and the prevention of candidal infections in patients with a weakened immune system.
Fluconazole can be used as maintenance therapy to prevent recurrence of cryptococcal meningitis in children at high risk of recurrence.
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Reviewed: October 15, 2023 by Francis Jameson