Severe hemoptysis in a critically ill patient must prompt rapid development of a broad differential. We present an unusual case…
Asking How Our Patients Understand Addiction
When the President’s Commission on Combating Drug Addiction and the Opioid Crisis declares “addiction [a] chronic relapsing disease of the…
Bilateral Breast Ulcers: Granulomatosis with Polyangiitis
An investigation into the patient’s unusual dermatologic symptoms identified an underlying autoimmune disease. Fourteen days after breast-reduction surgery, the patient,…
Sarcoidosis Presenting as Isolated Anasarca and Hypercalcemia
A 62-year-old woman presented to clinic for a second evaluation. Previously healthy, she initially presented for care several months earlier…
Spironolactone and Outcomes in Older Patients with Heart Failure and Reduced Ejection Fraction
The efficacy of mineralocorticoid receptor antagonists or aldosterone antagonists in heart failure with reduced ejection fraction (HFrEF) is well known.…
The Computerized ECG: Friend and Foe
Computerized interpretation of the electrocardiogram (ECG) began in the 1950s when conversion of its analog signal to digital form became…
Lift Then Shift: Thyrotoxic Periodic Paralysis
A transient paralysis was precipitated by thyroid dysfunction. The patient, a 29-year-old man, woke up with diffuse muscle pain and…
Down the Rabbit Hole: Cutaneous Tuberculosis
The term “going down the rabbit hole,” based on Lewis Carroll’s Alice’s Adventures in Wonderland, is a metaphor for an…
The Tradeoff of Cancer Drug Regulatory Policy: Faster Approvals for One Means Less Knowledge for Another
The popular narrative surrounding cancer drugs or other therapies for rare diseases is that patients are willing to assume more…
The Case for Confirmation: Atrial Flutter
Although computerized electrocardiogram (ECG) interpretation is a valuable and widespread clinical aid, it can be imperfect.1,2 The case of a…