Overstuffed cancer cells may have an Achilles’ heel

In a study using yeast cells and data from cancer cell lines, scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry genetic material. The vulnerability, they say, is rooted in a common feature among cancer cells — their high intracellular protein concentrations — that make them appear bloated and overstuffed, and which could be used as possible new targets for cancer treatments.

Dolutegravir Use at Conception — Additional Surveillance Data from Botswana

To the Editor: In May 2018, an unscheduled analysis from the Botswana–Harvard AIDS Institute Partnership Tsepamo birth-outcomes surveillance study showed a higher prevalence of neural-tube defects among infants born to women who were using dolutegravir-based antiretroviral treatment (ART) regimens…

Gun ownership linked to greater incidence of domestic homicides

A new study has reveals a unique and strong association between firearm ownership and the risk of domestic homicides. For each 10% increase in household gun ownership rates, the findings show a significant 13% increased incidence of domestic firearm homicide. The homicide risk differed across victim-offender relationships, with non-domestic firearm homicide rising only 2% among firearm owners.

More ED visits because of alcohol, 175% increase in 25- to 29-year-olds seeking care

New research shows dramatically rising visits to emergency departments (ED) related to alcohol, especially for women, with a 175% increase in alcohol-related visits from young people aged 25 to 29. The article shows increases in ED visits related to alcohol that are occurring much faster than overall ED usage.