An international team has shown how the Salmonella protein RamR senses bile acids present in the gut, leading to the activation of a multidrug efflux system that helps bacterial cells to get rid of toxins. This system helps the bacteria to survive and colonize this habitat despite harsh conditions. These findings could form the basis for new therapeutic approaches aimed at combating bacterial infection.
A simple new technique developed by engineers can detect fake drugs from a video taken as the sample undergoes a disturbance. Called ‘chronoprinting,’ the technology requires only a few relatively inexpensive pieces of equipment and free software to accurately distinguish pure from inferior food and medicines.
A researcher travels the Americas, collecting feces from nonhuman primates to determine the risk of Zika reservoirs.
New research investigates hot spots of genetic variation within the human genome, examining the sections of our DNA that are most likely to differ significantly from one person to another.
A team of researchers modeled the health and economic effects of healthy food prescriptions in Medicare and Medicaid. The study finds that health insurance coverage to offset the cost of healthy food for Medicare and/or Medicaid participants would be highly cost effective after five years and improve health outcomes.
As our collection of resident gut bacteria changes with age, it increasingly produces harmful metabolites that damage veins and blood vessels, driving disease, a new study suggests.
New work shows that an enzyme inhibitor reduced inflammation in the brains of mice born to mothers with maternal immune activation. Inflammation triggered by the enzyme, soluble epoxide hydrolase, is linked to neurodevelopmental disorders in these mice.
Researchers used C. elegans as an animal model to investigate the importance of certain human genes for the treatment of schizophrenia.
New insights into virus shell self-assembly could impact future drug delivery and therapeutic strategies.
The ability of the brain to ignore extraneous visual information is critical to how we work and function, but the processes governing perception and attention are not fully understood. Scientists have long theorized that attention to a particular object can alter perception by amplifying certain neuronal activity and suppressing the activity of other neurons (brain ”noise”). Now, scientists have confirmed this theory by showing how too much background noise from neurons can interrupt focused attention and cause the brain to struggle to perceive objects.