Gastroenterological disorders frequently lead to anaemia as a result of blood loss, inflammation, malabsorption or drug therapies. With malignancy or inflammatory bowel disease, the causes are often multifactorial. Aside from iron deficiency, other conditions resulting in vitamin B12 or folate deficiency can lead to anaemia. Here, coeliac disease, inflammatory bowel disease and surgical resection are particular risk factors. The approach to anaemia in the gastroenterology patient should focus on establishing and managing the underlying cause while supplementing any deficiencies to correct the anaemia.