To assess the factors associated with initiation and completion rates of Latent Tuberculosis infection treatment in persons evaluated at an infectious diseases outpatient clinic in central Massachusetts. The CDC estimates that there may be up to 14 million persons with latent tuberculosis infection in the US. The risk of developing active TB in these persons can range from 5 to 15%. Hence treatment of latent tuberculosis infection is an important aspect of any plan attempting to eliminate TB from the US.