The cryoEM structure of a simian immunodeficiency virus protein bound to primate proteins shows how a mutation in early humans allowed our ancestors to escape infection while monkeys and apes did not. SIV’s Nef protein forms a solid link between two primate proteins, tetherin and AP-2, forcing the destruction of tetherin, which normally prevents new SIV virions from budding off. A mutation in human tetherin disrupted binding, thwarting SIV budding — until HIV evolved a work-around.
Here’s how early humans evaded immunodeficiency viruses
Related Posts
Order Antibiotics online
June 8, 2024Buying antibiotics online
June 8, 2024How do antibiotics work?
June 8, 2024Flagyl: a beacon of hope in the fight against trichomoniasis
February 17, 2024
About admin
Now Dr. Jack Straw is in charge of the website, and organizes it so that medical care is available to everyone. In addition, he is an active member of the medical community, regularly attending international conferences and sharing his experience and knowledge.
Dr. Straw is not only a medical professional and website manager, but also a loving husband and father of his beautiful children.
View all posts by admin →