Female Patients with Sepsis Are Not Always Associated with a Higher Mortality Than Male Septic Patients

We read with great interest the article in an issue of The American Journal of Medicine by Seetharaman et al.1 The article concluded that the time to antibiotic administration in septic patients through the electronic medical record Best-Practice Advisory alerts did not affect the 30-day mortality rates, and female sex predicted mortality.1 However, we do not agree with these conclusions for several reasons.

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