Cholestasis (impairment of, or reduction in, bile flow) can both predispose to the development of chronic liver disease and result in its own specific symptoms. The severity of cholestatic symptoms (which themselves often impair quality of life) is typically independent of the severity of the underlying liver disease, the link with cholestasis therefore frequently being missed. The most characteristic symptoms of cholestasis are pruritus and fatigue, the former being the most responsive to treatment.
Complications of cholestasis
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