The Anti-Platelet Anomaly: Aspirin/Dipyridamole-Induced Acute Pancreatitis

Drug-induced pancreatitis is a rare etiology of pancreatitis, typically accounting for less than 2% of all incidents of acute pancreatitis.1 We present a case of aspirin/dipyridamole-induced pancreatitis in an elderly patient. There was no other evidence suggesting any other etiology of pancreatitis for this patient. According to the Naranjo Adverse Drug Reaction Probability Scale, the association of pancreatitis is a probable reaction due to aspirin/dipyridamole.2 Although rare, this severe complication illustrates how physicians and clinical pharmacists should be aware of the risk of pancreatitis with aspirin/dipyridamole and the consequences regarding secondary stroke prevention after it occurs.

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