Singapore saw 1,158 dengue cases in the week ending 13 June 2020, the highest number of weekly dengue cases ever recorded since 2014. The dengue virus serotype 3 (DENV3), which is currently circulating in Singapore, can undergo dramatic structural changes that enable it to resist vaccines and therapeutics, reveal findings from a new study. The findings could guide the development of effective vaccines and therapeutics against dengue infection.
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