Engineers have designed pliable, 3D-printed mesh materials whose flexibility and toughness they can tune to emulate and support softer tissues such as muscles and tendons. They can tailor the intricate structures in each mesh, and they envision the tough yet stretchy fabric-like material being used as personalized, wearable supports, including ankle or knee braces, and even implantable devices, such as hernia meshes, that better match to a person’s body.