Time-saving method makes it possible to profile gene regulation in tens of thousands of individual human cells in a single day. Approach combines microfluidics and novel software to scale up single-cell ATAC-seq, which identifies parts of the tightly packaged genome that are more open and accessible to regulatory proteins. Profiling individual cells can clarify how genes function – in which specific cell types, at what time – and whether they play a role in disease.
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