We read with interest the commentary on aspirin in primary prevention by Gitin et al.1 As ASPirin in Reducing Events in the Elderly (ASPREE) investigators, 1 of 3 key aspirin primary prevention trials referenced in this paper, we write to reiterate the unambiguous message from the ASPREE trial.2
Aspirin for Primary Prevention in Adults Older than 70 Years is Not Supported by High-Quality Trial Data and May Cause Harm
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