Acromegaly is a rare disease with an incidence of 3 per million per year. It is caused by pituitary hypersecretion of growth hormone and hepatic secretion of insulin-like growth factor-1 (IGF-1). Heart failure from acromegalic cardiomyopathy occurs in only ∼3% of these patients, and is the most common cause of death. We present a case of acromegalic cardiomyopathy which resolved following transsphenoidal surgery and removal of the pituitary microadenoma.