Elder abuse and adult safeguarding

This article defines elder abuse and describes its main categories. Risk factors and predictive indicators are discussed to help professionals identify older individuals who could be vulnerable. The adult safeguarding procedure, as defined by the UK Care Act 2014, is outlined, alongside the importance of a multidisciplinary approach to, as well as shared responsibility for, older adults at risk.

Practical advice for prescribing in old age

Optimizing drug therapy is an essential part of caring for older people. Prescribing in this group has unique challenges because of high interindividual variability in pharmacological response and homeostatic mechanisms, and the fact that frailty, rather than age, predicts physiological responses to external stimuli. The effects of drugs and how they are handled by the body change with increasing age. With decreasing life expectancy, drugs used for secondary prevention might not be appropriate, particularly where their adverse effects impair quality of life.

Chemists discover the structure of a key coronavirus protein

Chemists have determined the molecular structure of a protein found in the SARS-CoV-2 virus. This protein forms a cation-selective channel and plays a key role in the virus’s ability to replicate itself. If researchers could devise ways to block this channel, they may be able to reduce the pathogenicity of the virus and interfere with viral replication.