A new rhesus macaque animal model recapitulates the clinical and pathological manifestations of coronavirus disease 2019 (COVID-19) observed in humans by mimicking natural infection via the nasal route, according to a new study.
Category: Meds news
Re-mapping taste in the brain
A new study found that the map of neural responses mediating taste perception does not involve, as previously believed, specialized groups of neurons in the brain, but rather overlapping and spatially distributed populations.
In mice, cadmium exposure during pregnancy linked to obesity in female offspring
In a mouse study aimed at modeling human exposure to the toxic metal cadmium, researchers found that female offspring of mice exposed to cadmium during pregnancy became obese in adulthood, developed fatty livers and could not process glucose normally. Male offspring were not affected in the same way. The study also sheds light on how cadmium exposure could affect mitochondrial function and developmental signaling pathways in the liver.
Astrocytes identified as master ‘conductors’ of the brain
A team of scientists has found that glial astrocytes are involved in regulating inhibitory synapses by binding to neurons through an adhesion molecule called NrCAM.
Scientists pinpoint two new potential therapeutic targets for rheumatoid arthritis
A collaborative team of scientists has pinpointed two new potential therapeutic targets for rheumatoid arthritis – a painful inflammatory disease that affects an estimated 350 million people worldwide.
Americans likely to attend large holiday gatherings despite COVID-19, survey finds
A new national survey finds that although a majority of Americans plan to take precautions at holiday gatherings, such as social distancing and asking those with COVID symptoms not to attend, many will also put themselves at risk. Nearly two in five report they will likely attend a gathering with more than 10 people and a third will not ask guests to wear masks.
Repeated small blasts put military, law enforcement at risk for brain injury
Military and law-enforcement personnel repeatedly exposed to low-level blasts have significant brain changes – including an increased level of brain injury and inflammation — compared with a control group, a new study has found.
The Strategic Stockpile failed; experts propose new approach to emergency preparedness
A new analysis of the United States government’s response to COVID-19 highlights myriad problems with an approach that relied, in large part, on international supply chains and the Strategic National Stockpile. A panel of academic and military experts is instead calling for a more dynamic, flexible approach to emergency preparedness at the national level.
Audio Interview: An Update from Operation Warp Speed
The continuing spread of SARS-CoV-2 remains a Public Health Emergency of International Concern. What physicians need to know about transmission, diagnosis, and treatment of Covid-19 is the subject of ongoing updates from infectious disease experts at the Journal. In this audio interview conducted…
Rats are capable of transmitting hantavirus
Researchers have confirmed Germany’s first-ever case of animal-to-human transmission involving a specific species of virus known as the ‘Seoul virus’. Researchers were able to confirm the presence of the virus in a young female patient and her pet rat.