A 69-year-old man presented to the emergency department after the sudden onset of high fever and disorientation. His medical history included recurrent intraoral herpes. Neurologic examination revealed the presence of nuchal rigidity, with positive Brudzinski’s and Kernig’s signs. Lumbar puncture revealed a moderate increase in the level of protein in the cerebrospinal fluid, as well as a slight reduction in the level of glucose in the cerebrospinal fluid. Microscopic analysis of cerebrospinal fluid was unremarkable.