Obesity, risk of cognitive dysfunction? Consider high-intensity interval exercise

Researchers have discovered what might be an effective strategy to prevent and combat cognitive dysfunction in obese individuals. They are the first to examine the modulatory role of an exercise-induced protein in the brain that promotes neuron survival and used high-intensity interval exercise (HIIE) in obese and normal-weight subjects. Obesity reduces the expression of this protein and lower levels are associated with Alzheimer’s, Parkinson’s and obesity. HIIE upregulated this protein in the obese subjects compared to normal-weight subjects.

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