Science appears healthy on paper, but at what cost? Although the volume of published research doubles every 9 years1 retraction rates are increasing faster2. Recent studies find that up to 40% of researchers admit engaging in questionable research practices –involving shortening studies to give more favorable results, and ‘spinning’ negative results into positive findings3. Pressures are partly to blame: almost 60% of respondents to a national survey of scientific researchers in the United Kingdom reported being tempted or pressured to compromise their integrity and standards around scientific practices and reporting4.