A standalone attribute by most accounts, curiosity has much to offer the healing profession. Indispensable to any analytic efforts of a diagnostician, epistemic curiosity, also known as cognitive or intellectual curiosity, can hardly be overlooked. No other quality can be counted upon to rationalize seemingly insoluble clinical constellations. No other trait is likely to connect disparate clinical dots absent a conventional roadmap. Viewed in this light, curiosity constitutes an elemental trait of the practicing physician.