IMpact of Prolonged anticoagulation with Rivaroxaban On proVokEd Venous ThromboEmbolism recurrence: The IMPROVE-VTE Study

Venous thromboembolism, defined as deep-vein thrombosis or pulmonary embolism, is a major health concern in the United States (US), with over 900,000 thrombotic events reported each year, resulting in at least 600,000 hospitalizations and ∼100,000 deaths.1-3 Total treatment costs during the initial year after an index venous thromboembolism have been estimated to surpass $20,000 per patient.4

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