It’s a maddening cycle that has affected us all: it starts with an itch that triggers scratching, but scratching only…
Exercise-induced hormone irisin triggers bone remodeling in mice
Exercise has been touted to build bone mass, but exactly how it actually accomplishes this is a matter of debate.…
Neanderthal genes give clues to human brain evolution
A distinctive feature of modern humans is our round (globular) skulls and brains. Researchers report that present-day humans who carry…
Whether a urinary tract infection recurs may depend on the bacterial strain
Genetically diverse bacterial strains that cause urinary tract infections differ in their ability to trigger protective immune responses in mice,…
New interactions between Ebola virus and human proteins discovered
Several new connections have been discovered between the proteins of the Ebola virus and human host cells, a finding that…
Novel mechanisms of dengue and Zika virus infections and link to microcephaly
New insights into how dengue and Zika viruses cause disease reveal strategies the viruses use to successfully infect their host…
In the developing brain, scientists find roots of neuropsychiatric diseases
The most comprehensive genomic analysis of the human brain ever undertaken has revealed new insights into the changes it undergoes…
CRISPR joins battle of the bulge, fights obesity without edits to genome
A weighty new study shows that CRISPR therapies can cut fat without cutting DNA. Researchers describe how a modified version…
Noncoding mutations contribute to autism risk
A whole-genome sequencing study of nearly 2,000 families has implicated mutations in ‘promoter regions’ of the genome — regions that…
Scientists create genomic resource to explore biological underpinnings of brain disorders
Scientists have developed a model of unprecedented sophistication that relates variations in DNA and gene activity to the risk of…