Professional American-style football players are among the largest athletes across contemporary sporting disciplines. Weight gain during football participation is common,…
Advanced Therapies for Massive Pulmonary Embolism
The report by Secemsky et al1 in this issue of The American Journal of Medicine illustrates the current management of…
Introduction to Neurogenetics
Genetic variation can directly cause or increase susceptibility to neurologic diseases. An explosion of new genetic technologies has enabled the…
Serotonin Syndrome Masquerading as Ventricular Tachycardia Storm
A 60-year-old woman with bipolar disorder presented to a local hospital after being found unresponsive at home. When assessed by…
Misconceptions and Facts About Takotsubo Syndrome
Takotsubo Syndrome, initially described in the 1990s by Sato, has been increasingly recognized around the world. Pathophysiology is directed towards…
Reform in House Staff Working Hours and Clinical Supervision: A 30-Year Reflection Following the Release of the Bell Commission Report
When we were medical interns (WHF and JSA), training in 1969, the weekday work schedule on the ward services was…
See One, Be One, Teach One: How Becoming a Patient Informed My Role as a Teaching Physician
Many essays, books, and even movies have centered on the theme of doctor as patient. As an academic internist diagnosed…
Dementia and Atrial Fibrillation: Pathophysiological Mechanisms and Therapeutic Implications
Atrial fibrillation increases the risk of stroke by a factor of four- to fivefold, and dementia is a common consequence…
Role of High-Dose Beta-Blockers in Patients with Heart Failure with Preserved Ejection Fraction and Elevated Heart Rate
Beta-blockers in high target doses are recommended for heart failure with reduced ejection fraction (HFrEF) but not for preserved ejection…
Vitamin D Status and Exercise Capacity in Older Patients with Heart Failure with Preserved Ejection Fraction
Background: Older patients with heart failure with preserved ejection fraction have severe exercise intolerance. Vitamin D may play a role…